Oedema in kwashiorkor is caused by hypoalbuminaemia

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Oedema in kwashiorkor is caused by hypoalbuminaemia

It has been argued that the oedema of kwashiorkor is not caused by hypoalbuminaemia because the oedema disappears with dietary treatment before the plasma albumin concentration rises. Reanalysis of this evidence and a review of the literature demonstrates that this was a mistaken conclusion and that the oedema is linked to hypoalbuminaemia. This misconception has influenced the recommendations ...

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Mechanisms of oedema formation: the minor role of hypoalbuminaemia.

OBJECTIVES Seriously ill patients often suffer from disorders of salt and water balance and present with clinical signs of either dehydration or oedema. The relationship of hypoalbuminaemia to oedema is complex and controversial and formed the central issue of this study. DESIGN Prospective study. SETTING Medical wards of New Somerset Secondary Hospital, November 2004. SUBJECTS 50 patient...

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Plasma free iron: a possible cause of oedema in kwashiorkor.

BACKGROUND Oedema is a sine qua non for the diagnosis of kwashiorkor yet the mechanisms leading to oedema remain ill defined. AIMS To relate the plasma concentration of radical promoting 'free' iron to the degree of oedema in patients with kwashiorkor. SETTING University teaching hospital. PATIENTS Fifteen children with kwashiorkor, nine of whom had severe and six of whom had a moderate d...

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Kwashiorkor: more hypothesis testing is needed to understand the aetiology of oedema.

Epidemiology Kwashiorkor is almost never seen in the developed world. Widespread in sub-Saharan Africa and common in Southeast Asia and Central America, kwashiorkor occurs in young children living in areas with endemic food insecurity or famine; prevalence varies by geographic area, with reported levels ranging up to 6% in some chronic foodinsecure communities and occasionally to one quarter of...

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Unilateral oedema of the lower limb caused by an osteochondroma.

There was uniform swelling of the left lower limb from the toes to the inguinal region. The girth of the left calf was 2 cm greater than that of the right. Dilated venules and arbourising telangiectasia were noted over the front of the leg. A localised swelling, firm and immobile, was discovered in the left inguinal region; the skin appeared normal over this swelling and was not tethered. Plain...

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ژورنال

عنوان ژورنال: Paediatrics and International Child Health

سال: 2014

ISSN: 2046-9047,2046-9055

DOI: 10.1179/2046905514y.0000000154